Technology & Innovation
Bag-on-Valve Nasal Sprays: Preservative-Free by Design
How do seawater nasal sprays stay preservative-free and work upside down? The answer is bag-on-valve technology: a sealed inner bag that keeps the product away from air and propellant.
Behind every good seawater nasal spray there is a good container. All Neomedis sprays use bag-on-valve (BoV) technology, a dispensing system that protects the product, removes the need for preservatives and gives a better spray. Here is how it works.
What is a bag-on-valve spray?
In a traditional aerosol, the product and the propellant are mixed in the same can. In a bag-on-valve spray, the product is sealed inside a flexible bag welded to the valve. The propellant stays outside the bag and simply squeezes it: when you press the nozzle, the product is pushed out, without ever being in contact with the propellant or the outside air.
Why it matters for a nasal spray
- Ultimate protection: a four-layer bag provides a strong barrier function around the product.
- Complete separation of the product from the propellant, and non-VOC (volatile organic compound) propellants.
- Preservative-free: all Neomedis bag-on-valve sprays are preservative-free.
- Anti retro-contamination: the sprays are technically proven to prevent contamination from flowing back into the container.
- Efficient: up to 99.7% of the product is evacuated, so almost nothing is wasted.
Easier to use, at any angle
- Continuous dispensing system: a uniform, wide and continuous nebulisation.
- Works at any angle, including upside down (360° spray): practical for babies lying down.
- Available in 50 ml, 100 ml and 125 ml presentations.
Actuators designed for the nose
The standard actuators are industrially mounted and cannot be removed. They include an integrated “stopper” that prevents deep insertion into the nostrils, which makes them better suited to babies and children, and they are tamper-evident. They are available in all delivery rates, from 0.7 to 7.5 ml/s, and in several colours.
Optional actuators complete the offer: SOFT for babies, and DUO for families, which switches between nebulisation and jet spray.
Bag-on-valve and natural seawater: a natural fit
Because the bag keeps the formula sealed from air until the last spray, natural seawater from Brittany can be packed without any preservative, from the isotonic HYPOMER® SOFT and BABY to the hypertonic and xylitol formulas. Explore the full product range.
Bag-on-valve nasal sprays in private label
For a private label project, the container is part of the brand: format, actuator, delivery rate and colour can be chosen to match the target users. Neomedis gives access to these innovative dispensing technologies as part of its private label offer. Preview your bottle and box in the simulator or read how to choose a private label nasal spray manufacturer.
Frequently asked questions
Why are bag-on-valve nasal sprays preservative-free?
The product is sealed in a multi-layer bag, separated from the propellant and from the outside air, and the system prevents retro-contamination. The formula therefore does not need preservatives.
Can a bag-on-valve spray be used upside down?
Yes. It works at any angle (360°), with a continuous and uniform spray.
Which formats are available?
50 ml, 100 ml and 125 ml, with standard actuators in delivery rates from 0.7 to 7.5 ml/s, and optional SOFT and DUO actuators.



