Technology & Innovation
Xylitol Nasal Spray: How Seawater and Xylitol Work Together
Why add xylitol to a seawater nasal spray? Bacteria, biofilms and the patented ZYLOMER® formula explained: the science behind a new generation of natural nasal sprays.
Seawater sprays clean the nose. But can a nasal spray also help prevent bacteria from settling in? That is the idea behind the xylitol nasal spray. Neomedis designed and developed the ZYLOMER® range, which combines natural seawater with xylitol in a patented formula.
What is xylitol?
Xylitol is a sugar alcohol of natural origin, well known for its use in dental care. Neomedis uses raw, pharmaceutical-grade xylitol of natural origin. It is GMO-free, BSE/TSE-free, melamine-free and pesticide-free, with no residual solvents and no starch or gluten.
How bacteria settle in the nose
Pathogenic bacteria such as staphylococci constantly look for a surface to anchor to, because resting on tissue requires much less energy than floating freely. Colonisation follows four steps:
- Attachment: a single bacterium enters the nose and anchors to the nasal tissue.
- Reproduction: it divides rapidly, forming clusters of identical cells.
- Matrix creation: the clusters produce a sticky slime to shield themselves.
- Mature biofilm: a protective film seals the bacteria in and holds them on the inside of the nose.
These biofilms act as reservoirs that can fuel recurring ENT infections. A simple saline spray, made of water and sodium chloride, rinses away loose dirt but leaves established biofilms untouched.
How xylitol works against bacterial adhesion
Bacteria mistake xylitol for a nutrient such as glucose and absorb it. But they cannot break it down: they spend their energy expelling it, then take it up again. Weakened by this futile cycle, they struggle to produce the sticky matrix they need to anchor themselves. In short, xylitol prevents harmful bacteria from adhering to the nasopharyngeal mucous membrane, which contributes to reducing bacterial infections and facilitates the respiratory functions of the nose.
Seawater + xylitol: what each brings
| Function | Standard saline | Seawater + xylitol |
|---|---|---|
| Mechanical cleansing of mucus | Yes | Yes |
| Mineral hydration of the nasal tissue | No | Yes |
| Inhibition of bacterial adherence | No | Yes |
| Action on existing biofilms | No | Yes |
Natural seawater adds its own benefits: its magnesium, calcium and manganese ions help soothe inflamed tissue, nourish the nasal cilia and support the repair of membranes irritated by pollution or inflammation.
The ZYLOMER® range: three patented formulas
- ZYLOMER® DEFEND, “the umbrella formula”: 21% natural seawater and 11% xylitol, for the daily cleaning of the nasal cavity and the prevention of bacterial infections, from 3 months.
- ZYLOMER® BABY: the same seawater and xylitol formula for babies over 3 months and children.
- ZYLOMER® ATTACK, “the lightning rod formula”: hypertonic, 68% natural seawater and 11% xylitol, to clear the nose and help prevent bacterial infections during episodes of congestion, from 3 years.
According to Neomedis, ZYLOMER® is the only nasal spray line in the world that combines seawater and xylitol. All three formulas are 100% natural, preservative-free and manufactured in France. They have a natural, slightly sweet aftertaste, and a temporary tingling sensation may occur during the first uses. Discover the whole prevention range.
Patented nasal sprays: a differentiating offer
For distributors and healthcare brands, patented nasal sprays are a way to stand out in a crowded seawater category. The ZYLOMER® formulas are available for distribution and for private label projects. Become a distributor or tell us about your project.
Frequently asked questions
What does xylitol do in a nasal spray?
Xylitol prevents harmful bacteria from adhering to the nasal mucosa, which helps reduce bacterial infections, while seawater cleanses and hydrates the nose.
Can a xylitol nasal spray be used every day?
Yes. ZYLOMER® DEFEND and ZYLOMER® BABY are intended for daily nasal hygiene, from 3 months. ZYLOMER® ATTACK is used during episodes of congestion, from 3 years.
Why does the spray taste slightly sweet?
Xylitol is a sugar alcohol of natural origin: the ZYLOMER® formulas have a natural sweet aftertaste.
Is the ZYLOMER® formula patented?
Yes. The combination of seawater and xylitol used in ZYLOMER® is patented by Neomedis.
